Brace for potentially devastating typhoon approaching PH – NDRRMC PH squash team after their 2017 SEA Games gold medal match. Photo by Marc ReyesKUALA LUMPUR—The Philippine men’s squash team, which upset Malaysia in the semifinals on Monday, surrendered to Singapore, 2-1, in the final Tuesday night at National Squash Center here in Kuala Lumpur Sports Center.The Filipinos settled for another silver, the other in women’s doubles, in the penultimate day of competition.ADVERTISEMENT Read Next Catriona Gray spends Thanksgiving by preparing meals for people with illnesses Typhoon Kammuri accelerates, gains strength en route to PH LATEST STORIES UPLB exempted from SEA Games class suspension Don’t miss out on the latest news and information. PH billiards team upbeat about gold medal chances in SEA Games PLAY LIST 03:07PH billiards team upbeat about gold medal chances in SEA Games05:25PH boxing team determined to deliver gold medals for PH00:59Sports venues to be ready in time for SEA Games00:50Trending Articles01:35Panelo suggests discounted SEA Games tickets for students02:49World-class track facilities installed at NCC for SEA Games03:04Filipino athletes share their expectations for 2019 SEA Games00:45Onyok Velasco see bright future for PH boxing in Olympics02:25PH women’s volleyball team motivated to deliver in front of hometown crowd01:27Filipino athletes get grand send-off ahead of SEA Games LOOK: Venues for 2019 SEA Games MOST READ WATCH: Streetboys show off slick dance moves in Vhong Navarro’s wedding Kammuri turning to super typhoon less likely but possible — Pagasa Filipinos bag another silver in sepak takraw Reymark Bergornia dropped the opening match, 11-1, 11-3, 11-16, to Pang Ka Hoe. But Robert Andrew Garcia equalised after beating Benedict Chan, 11-8, 9-11, 11-8, 11-9, in the second match.That left David William Pelino to carry the fight for the gold but he succumbed to the faster and craftier Samuel Kang, 11-4, 11-4, 11-5, in the deciding match.FEATURED STORIESSPORTSWATCH: Drones light up sky in final leg of SEA Games torch runSPORTSSEA Games: Philippines picks up 1st win in men’s water poloSPORTSMalditas save PH from shutout SEA Games in Calabarzon safe, secure – Solcom chief View comments
Don’t miss out on the latest news and information. Photo by Tristan Tamayo/INQUIRER.netMANILA, Philippines—Mike Gamboa is going to get another year of living his PBA dream.The diminutive 5-foot-6 guard signed a one-year deal with current club Phoenix in what he described as the culmination of all his hard work.ADVERTISEMENT Private companies step in to help SEA Games hosting SEA Games hosting troubles anger Duterte View comments SEA Games: Biñan football stadium stands out in preparedness, completion Hotel management clarifies SEAG footballers’ kikiam breakfast issue Trending Articles PLAY LIST 00:50Trending Articles00:50Trending Articles00:50Trending Articles02:42PH underwater hockey team aims to make waves in SEA Games01:44Philippines marks anniversary of massacre with calls for justice01:19Fire erupts in Barangay Tatalon in Quezon City01:07Trump talks impeachment while meeting NCAA athletes02:49World-class track facilities installed at NCC for SEA Games02:11Trump awards medals to Jon Voight, Alison Krauss SEA Games: Biñan football stadium stands out in preparedness, completion Blackwater taps Rommel Adducul as big man coach “Thank you to God, my family, mom and dad I love you! My supportive brothers I love you all. And to everyone who has helped me in this journey,” said Gamboa through social media. “To my fiancé Carmen and baby Mikee, you’re the reason why I made it and each practice/game is dedicated to you! I love you both! Let’s go Phoenix!”Gamboa started his basketball career at Ateneo before moving to University of the Philippines in the UAAP but decided he would go into the corporate life when he graduated in 2013.FEATURED STORIESSPORTSPrivate companies step in to help SEA Games hostingSPORTSUrgent reply from Philippine football chiefSPORTSSEA Games: Biñan football stadium stands out in preparedness, completionFollowing a year of working in an office, Gamboa tirelessly worked hard in achieving the dream he almost lost. He eventually became the ninth pick in the second round of the 2014 PBA Rookie Draft by Rain or Shine.Gamboa, however, wasn’t signed and he went on to play for Bread Story and Hapee in the PBA D-League. He also played for Pilipinas MX3 in the ASEAN Basketball League in 2016. LATEST STORIES TS Kammuri to enter PAR possibly a day after SEA Games opening Sports Related Videospowered by AdSparcRead Next The year 2017, though, was the toughest for Gamboa as he was an almost invisible figure basketball circles until Phoenix head coach Louie Alas sent him an invite to try out for the Fuel Masters.It was also at this time that Gamboa found out he was about to be a father, and the looming family life was what ignited the fire within the point guard’s heart.“Everyone kept on telling me what my plan should be and I should start facing reality,” said Gamboa. “Only my girlfriend and a few friends believed that I was still going to make it to the PBA, it was then I always asked God why He put me back to playing basketball again.”“I found out that my girlfriend was pregnant and immediately finding out that I was going to be a father, I had that fire back and I knew I had to give it one last shot for my future baby and family.”Gamboa played a total of 12 games for the Fuel Masters in the 2017-18 season, averaging 2.1 points, 0.6 rebounds, and 1.3 assists.ADVERTISEMENT Is Luis Manzano planning to propose to Jessy Mendiola? MOST READ LOOK: Joyce Pring goes public with engagement to Juancho Triviño
Charlotte Hornets owner and former North Carolina great Michael Jordan, center, watches North Carolina play Virginia during an NCAA college basketball game in Chapel Hill, N.C., Monday, Feb. 11, 2019. At right is former North Carolina player Buzz Peterson, assistant general manager of the Hornets, and at left is former North Carolina player Mitch Kupchak, general manager of the Hornets. Peterson knew Jordan as well as anyone when they were in college. Roommates and teammates at North Carolina, they spent countless days competing on the basketball court in practice and endless hours talking hoops. But Peterson never saw this coming: His roommate becoming an NBA owner and hosting the league’s All-Star game in his home state of North Carolina. (AP Photo/Gerry Broome)CHARLOTTE, N.C. — Buzz Peterson knew Michael Jordan as well as anyone when they were in college.Roommates and teammates at North Carolina, they spent countless days competing on the basketball court in practice and endless hours talking hoops. Their nights often included shooting pool and tossing cards in their Granville Towers South dorm room. There often were arcade games — before the home video game craze hit — at the Pump House on Franklin Street in downtown Chapel Hill.ADVERTISEMENT Forbes Magazine estimated Jordan’s net worth in 2018 at $1.6 billion.“Remarkable,” Peterson said, “you almost have to pinch yourself.”Dell Curry says Jordan wants nothing but the best in anything he does — including this weekend’s All-Star game.“He’s excited for the NBA to come to his home state and play in the building of the team he owns,” said Curry, the Hornets color commentator and former NBA player. “So he is going to roll out the red carpet. He only knows one way to do it, and that is big time.”Added James Jordan: “I think when it’s all over, he will sit back and relax and maybe smoke a cigar and say ‘that was a great event,’ and just be really proud of himself that he made it happen.”Sports Related Videospowered by AdSparcRead Next Grace Poe files bill to protect govt teachers from malicious accusations MOST READ “Michael has always been very sharp, very smart,” said Peterson, who now works as an assistant general manager for Jordan’s Charlotte Hornets. “He’s a very good listener. He gathers information and opinions and then makes decisions. And once he makes the decision to go after something, he goes all out. He is absolutely driven to be successful in whatever he chooses.”It’s well-known that Jordan uses failure to motivate him.The only thing seemingly that has eluded Jordan, who turns 56 on Sunday — the day of the All-Star game — is ultimate success as an executive and team owner.His Hornets have yet to win a playoff series since he took over as majority owner nine years ago and they remain mired in NBA mediocrity while struggling to compete in a small market.But Jordan wants to keep his team — and the city — relevant. It’s one reason he aggressively pursued the All-Star game with such vigor.ADVERTISEMENT Don’t miss out on the latest news and information. But Peterson never saw this coming: His roommate becoming an NBA owner and hosting the league’s All-Star game in his home state of North Carolina.“You know, staring across the dorm room at him back then, no, I never would have thought this would happen,” Peterson told The Associated Press.FEATURED STORIESSPORTSPrivate companies step in to help SEA Games hostingSPORTSUrgent reply from Philippine football chiefSPORTSPalace wants Cayetano’s PHISGOC Foundation probed over corruption chargesThat’s understandable; they were young kids who didn’t know any better.Looking back now, Peterson said he should have known what Jordan’s parents instilled in him: He could achieve anything and he was destined for something extraordinary. “I think getting the All-Star game here is an accomplishment that will go on his list, and it will stand out for him because it’s really not about him,” said James Jordan Jr., Michael’s older brother. “This is an event that’s bigger than him. It’s really about the world — and he’s going to be the host of it.”On the court, after not being able to make his school varsity as a sophomore, he went on to become a two-time All-American, NCAA champion and the national college player of the year in 1984. He is a two-time Olympic gold medalist and won three straight NBA titles — and after a stint in minor league baseball — returned to the league and won three more.Off the court, Jordan marketed his on-court success into a fortune.“He has always had incredible determination — always,” said Fred Lynch, Jordan’s former junior varsity basketball coach at Wilmington’s Laney High School.James Jordan Jr. said it comes from their parents.He describes Michael as a “country boy” who never lost sight of his work ethic. He was the youngest of the three boys who relished a challenge, and James Jr. said their parents, James Sr. and Deloris Jordan, always taught the boys to go after their dreams.“Our parents taught us that you can achieve anything you want, but you have to have drive, that motivation — and you have to work hard at it,” said James Jordan Jr., who now works as an executive for the Hornets after spending 31 years in the military.Jordan changed the shoe game when Nike created Air Jordan, which he later spun off into the Jordan Brand.Now, when fans see the Jumpman logo, they think of Jordan.“I think it was easy to envision Michael doing anything at that point,” said former Chicago Bulls teammate Steve Kerr. “He was conquering the NBA world as a player and as a shoe salesman and endorser, so I think we all just felt like the sky was the limit. So this (hosting an All-Star game) is not that surprising to me at all.” PH underwater hockey team aims to make waves in SEA Games PLAY LIST 02:42PH underwater hockey team aims to make waves in SEA Games01:44Philippines marks anniversary of massacre with calls for justice01:19Fire erupts in Barangay Tatalon in Quezon City01:07Trump talks impeachment while meeting NCAA athletes02:49World-class track facilities installed at NCC for SEA Games02:11Trump awards medals to Jon Voight, Alison Krauss ‘We are too hospitable,’ says Sotto amid SEA Games woes Oil plant explodes in Pampanga town Oil plant explodes in Pampanga town ‘We are too hospitable,’ says Sotto amid SEA Games woes US judge bars Trump’s health insurance rule for immigrants SEA Games hosting troubles anger Duterte Private companies step in to help SEA Games hosting LATEST STORIES Regine Arocha delivers another performance worthy of NCAA volleyball Finals MVP View comments
Oklahoma State and Kansas State played a hell of a football game on Saturday afternoon in Manhattan. It was a game that left Glenn Spencer saying, “How did we win that game?” If you simply look at the drive charts, you will be wondering the same thing. Let’s dive in.OSU Drive ChartOklahoma State started off in the first half but went four straight drives in the middle without a point and had two punts and two turnovers. Then it ended the way it began — with a batch of TDs.Yards per play: 10.0Points per drive (offense): 3.58Points per drive (defense): 2.50Points off turnovers: 0Average starting field position: Own 19One area in which Oklahoma State has really thrived this year is the field position game. This was not the case on Saturday as Kansas State started a full 14 yards better than the Pokes. It was not a banner day for either defense although OSU held KSU to around its average (2.44 PPD).Note: I had this incorrect in my 10 Thoughts as I forgot about the pick-six which obviously doesn’t go to the offense.Oklahoma State went 247 yards in its final three scoring drives in just 15 plays or 16.5 yards per play. That is strong. That is finishing like Rob Glass is your conditioning coach.“We stress never showing any fear, never showing any fatigue, and never showing any frustration in our organization,” said Gundy after the game. “Two of those came to light by not showing frustration, from the coaches or players, we are not allowed to show frustration. I thought the fatigue in the latter part of the game that we were in better condition and more fresh than they [Kansas State] were today.”Kansas State Drive ChartGiving up 16 points in the first four drives to a team that almost literally does not pass is not how you want to roll if you’re Oklahoma State. Neither is that 0-play, 0-yard drive in the third quarter.Yards per play: 5.8Points per drive (offense): 2.50Points per drive (defense): 3.58Points off turnovers: 7Average starting field position: Own 33Kansas State didn’t really capitalize on the turnovers it created netting just seven points off of three turnovers. To contrast Oklahoma State’s final three scoring drives, Kansas State had 17 just 68 yards on 17 plays in its final three drives when OSU desperately needed stops.The Pokes won the game when the chips were down late in the fourth quarter. Something they seem to have a history of doing. While you’re here, we’d like you to consider subscribing to Pistols Firing and becoming a PFB+ member. It’s a big ask from us to you, but it also comes with a load of benefits like ad-free browsing (ads stink!), access to our premium room in The Chamber and monthly giveaways.The other thing it does is help stabilize our business into the future. As it turns out, sending folks on the road to cover games and provide 24/7 Pokes coverage like the excellent article you just read costs money. Because of our subscribers, we’ve been able to improve our work and provide the best OSU news and community anywhere online. Help us keep that up.
While you’re here, we’d like you to consider subscribing to Pistols Firing and becoming a PFB+ member. It’s a big ask from us to you, but it also comes with a load of benefits like ad-free browsing (ads stink!), access to our premium room in The Chamber and monthly giveaways.The other thing it does is help stabilize our business into the future. As it turns out, sending folks on the road to cover games and provide 24/7 Pokes coverage like the excellent article you just read costs money. Because of our subscribers, we’ve been able to improve our work and provide the best OSU news and community anywhere online. Help us keep that up. Do you ever watch an OSU game and think, “This is taking forever?”There’s a reason for that. College football games are at an all-time high in terms of length and Oklahoma State games take the longest. Dennis Dodd of CBS Sports wrote a very interesting piece on that phenomenon and its contributing factors.Oklahoma State ranked first (or last, depending on how you look at it) in average game length at 3:57. He did qualify the two back-to-back weather delays against Pitt and Baylor. If you remove those, the Cowboys are still ninth on his list.“An average Oklahoma State game lasts three minutes short of that four-hour mark. The Wall Street Journal in September reported it was possible to fly from Los Angeles to Washington, D.C. in less time than it took to play a college football game.”He brings a very interesting point that “fast-paced” offenses actually tend to drag the overall length of the game out. It makes senses. With each first down, each incomplete pass, each score, each change of possession you’re stopping the clock.Another reason given is the steady increase in the use of official reviews.“A record 727 games last season included at least one review stoppage. Through nine weeks, that record was on pace to be shattered — 765 games before the bowls even kick off.”Big 12 commissioner and chairman of the NCAA’s Football Oversight Committee offered a possible solution.“If we decided we weren’t going to kick off anymore or only kickoff in certain situations, you save a fair amount of time then,” said Bowlsby, also the Big 12 commissioner. “That’s exactly why we put the oversight committee together — to take a holistic look at it. It’s going to continue to be on our agenda.”Whether such drastic changes are made or not, it does not appear that game length has negatively affected TV ratings. Although this weekend’s game against Texas Tech which could legitimately last five hours might challenge that.What about you? How do you feel about committing half of your Saturday to watch a football game? Let us know how you feel in the comment section.
16Taj WilliamsTCUJr.WR93364319.48 26Josh MaloneTennesseeJr.WR103564818.51 25Deandre ThompkinsPenn St.So.WR91935318.58 1Jalen RobinetteAir ForceSr.WR102876027.14 19Carlos HendersonLouisiana TechJr.WR1061117919.33 21Jimmy WilliamsEast CarolinaSr.WR103771119.22 RankNameTeamClPositionGRecRec YdsAvg 6Jon’Vea JohnsonToledoSo.WR103470020.59 24Cedrick WilsonBoise St.Jr.WR104482718.80 3Jaylen SmithLouisvilleSo.WR102248722.14 While you’re here, we’d like you to consider subscribing to Pistols Firing and becoming a PFB+ member. It’s a big ask from us to you, but it also comes with a load of benefits like ad-free browsing (ads stink!), access to our premium room in The Chamber and monthly giveaways.The other thing it does is help stabilize our business into the future. As it turns out, sending folks on the road to cover games and provide 24/7 Pokes coverage like the excellent article you just read costs money. Because of our subscribers, we’ve been able to improve our work and provide the best OSU news and community anywhere online. Help us keep that up. 2Jeff BadetKentuckyJr.WR102354523.70 11Chico McClatcherWashingtonSo.WR92040120.05 7Cody ThompsonToledoJr.WR1050102120.42 13Deon CainClemsonSo.WR102549419.76 14Donald GrayMississippi St.Jr.WR103058719.57 4Ahmmon RichardsMiami (FL)Fr.WR103473221.53 5Jester WeahPittsburghJr.WR102860121.46 10James WashingtonOklahoma St.Jr.WR1056113220.21 22Josh ReynoldsTexas A&MSr.WR103974119.00 12Shelton GibsonWest VirginiaJr.WR93570120.03 20Stephen LouisNorth Carolina St.So.WR102446319.29 27Dede WestbrookOklahomaSr.WR1068125418.44 18Deangelo YanceyPurdueSr.WR103771819.41 23RJ TurnerLa.-MonroeSo.WR102343318.83 James Washington has been named one of ten semifinalists for the Biletnikoff Award, which is given to the country’s most outstanding receiver regardless of position. Washington has recorded 56 receptions for 1132 yards and 9 touchdowns this season. Here are the other semifinalists that were named Monday morning:Austin Carr, NorthwesternCorey Davis, Western MichiganAmba Etta-Tawo, SyracuseCarlos Henderson, Louisiana TechIsaiah “Zay”Jones, East CarolinaJohn Ross, WashingtonTaywan Taylor, Western KentuckyTrent Taylor, Louisiana TechJames Washington, Oklahoma StateDede Westbrook, OklahomaWashington is No. 8 in total receiving yards on the season in the country, but what hurts him is his volume. He ranks 41st in total receptions per game with just 5.6 receptions per game. That’s a testament to what he has been able to do in his limited touches, still sitting in the top 10 in total receiving yards per game at 113.2.Here is how he stacks up in yards per reception (via NCAA.com) 17Kevin KutcheraSouth Ala.Sr.WR92446619.42 15Kevin StephersonNotre DameFr.DB102141019.52 9Mikah HolderSan Diego St.Jr.WR92142620.29 The three Biletnikoff finalists will be announced on Nov. 21, and the award winner will be named on Dec. 8 on the Home Depot College Football Awards Show. 8Josh StewartUTSAJr.WR102959120.38
The Packers finished last season with a 12-7 record and, after opening the season 4-6, rode an 8-game winning streak that ended in a loss in the conference championship to the Atlanta Falcons.A former Louisiana-Monroe cornerback, Pipkins jumped into OSU’s rotation at cornerback last season at a time it desperately needed experience. He was a mainstay in the defensive backfield and another in a long line of graduate transfers to make an impact for OSU. He recorded 24 solo tackles, 14 assisted tackles, one tackle for loss, one interception and one pass breakup in the 2016-17 season. Lenzy Pipkins has joined the fraternity of former OSU players who were not selected in the NFL Draft but have since signed as an undrafted free agent, joining Jordan Sterns, Blake Jarwin, Ashton Lampkin and Jhajuan Seales. Pipkins, who spent just one season in Stillwater, announced the Green Bay Packers are giving him a shot at the next level.For those teams that passed me up thank you bc its go time now thank you Green Bay Packers organization for the opportunity ??— Lenzy Pipkins (@Pippy_LONGsock) April 29, 2017 While you’re here, we’d like you to consider subscribing to Pistols Firing and becoming a PFB+ member. It’s a big ask from us to you, but it also comes with a load of benefits like ad-free browsing (ads stink!), access to our premium room in The Chamber and monthly giveaways.The other thing it does is help stabilize our business into the future. As it turns out, sending folks on the road to cover games and provide 24/7 Pokes coverage like the excellent article you just read costs money. Because of our subscribers, we’ve been able to improve our work and provide the best OSU news and community anywhere online. Help us keep that up.
In honor of Mike Gundy’s 50th birthday last weekend, it only seemed right to look back at his 50th win as the head coach of Oklahoma State. Luckily, it just so happened to be one of the craziest games OSU has ever played. Not because of the score, but because it almost never kicked off.For those who don’t remember, on September 17th, 2011, OSU was in Tulsa set to kick-off against the Golden Hurricanes in the third week of the season. The game had been scheduled to start at 9:10 p.m. (because T.V.) but due to a storm system that rolled into town, didn’t officially kick off until 12:16 a.m. Central time on September 18, 2011.Had the game suffered one more lightning delay, it would have been canceled.AdChoices广告Instead, fans who didn’t have a ticket were allowed to enter the rain soaked Tulsa stadium for free and enjoy some late night early morning football.As to be expected after a three-hour delay, the Cowboys came out a little sluggish. On the opening drive, Brandon Weeden threw an interception that the Golden Hurricanes turned into three points. That seemed to jolt the Cowboys awake. Justin Gilbert returned the ensuing kickoff 96 yards for a touchdown and OSU never looked back.OSU led 31-6 at halftime, and 45-6 midway through the third quarter before Tulsa ripped off three touchdowns on their next three possessions. It didn’t help Tulsa any that they lost their starting quarterback to injury in the first quarter.When the game officially ended, the score was 59-33 and the clock read 3:35 a.m.“When we won the game, everybody’s obviously very excited about the game but everybody’s just walking around like zombies,” Weeden said. “Everybody’s pretty fatigued.” While you’re here, we’d like you to consider subscribing to Pistols Firing and becoming a PFB+ member. It’s a big ask from us to you, but it also comes with a load of benefits like ad-free browsing (ads stink!), access to our premium room in The Chamber and monthly giveaways.The other thing it does is help stabilize our business into the future. As it turns out, sending folks on the road to cover games and provide 24/7 Pokes coverage like the excellent article you just read costs money. Because of our subscribers, we’ve been able to improve our work and provide the best OSU news and community anywhere online. Help us keep that up. Notes from the game:• Justin Blackmon’s NCAA record run of 14 triple-digit receiving yard games ended this night. He totaled 57 yards and a touchdown.• The NCAA doesn’t keep records for latest start or finish times, but this one had to have been in the top 3.• On a sad note, this was the game then defensive line coach Glenn Spencer lost his wife Angela. He had to rush back to Stillwater and missed the game.• Fun fact! This year’s season opener is the final game of a three game deal that included the 2011 game in Tulsa and the 2010 game in Stillwater. This year’s game was supposed to have been played a few years ago, but was rescheduled for either the Mississippi State game or the Florida State game. I can’t remember which.• Just hours after this game was over Pittsburgh and Syracuse announced they were leaving the now defunct Big East football conference for the ACC. Speaking of Pitt, we play them Week 3 this season!• The kickoff attendance of the game was an estimated to be 18,000 to 20,000. Can you imagine waiting three hours at TU’s stadium until after midnight to watch a college football game?• If Oklahoma State beats Tulsa this year, the six-game win streak will be the largest for either team in the series.
Transfers Heynckes shoots down Lewandowski to Madrid rumours: Top players stay at Bayern Ryan Benson Last updated 1 year ago 15:52 24/2/2018 FacebookTwitterRedditcopy Comments(5) Transfers Real Madrid Robert Lewandowski Primera División Bayern München Bundesliga Videos The Polish striker changed his agent in recent days to prompt suggestions that he was ready to leave the Bundesliga giants in the summer Jupp Heynckes claims he “can’t imagine” Bayern Munich sanctioning the sale of Robert Lewandowski after the striker’s recent change of agent prompted fresh transfer links with Real Madrid.Lewandowski is said to have severed ties with Cezary Kucharski, previously his agent for 10 years, in favour of Pini Zahavi, regarded as one of the football world’s leading representatives.Zahavi played a role in Neymar’s world-record €222 million switch from Barcelona to Paris Saint-Germain in August and there have been suggestions Lewandowski’s decision has been made with a view to securing a big move to Spain. Editors’ Picks Williams case shows Solskjaer isn’t holding Man Utd’s youngsters back – he’s protecting them Goalkeeper crisis! Walker to the rescue but City sweating on Ederson injury ahead of Liverpool clash Out of his depth! Emery on borrowed time after another abysmal Arsenal display Diving, tactical fouls & the emerging war of words between Guardiola & Klopp Heynckes is not worried about such a scenario, however, and is adamant Bayern are not a selling club.When it was put to Heynckes that Lewandowski’s decision could be to secure a transfer, the coach said: “Well, that’s your interpretation.”I think there’s nothing wrong with a player changing his agent. I can’t judge the reasons.”It doesn’t mean anything at all for us, given the way I know the officials here at Bayern and what I’ve heard from them.”Bayern is not a club that sells the top players. Top players at Bayern stay at Bayern. I can’t imagine there’s a chance of him leaving Bayern.”
Atlético Madrid Simeone: Adding Costa has improved Griezmann’s form Jamie Smith 09:58 1/3/2018 FacebookTwitterRedditcopy Comments(1) Getty Images Atlético Madrid Antoine Griezmann Leganés Atlético Madrid v Leganés Primera División The French forward struck four goals in a brilliant performance against Leganes, and his manager thinks his strike partner has helped his form Diego Simeone believes the January introduction of Diego Costa into the Atletico Madrid first team has helped Antoine Griezmann move to the next level with an extraordinary period of goalscoring form.Griezmann struck all four goals in a 4-0 defeat of Leganes in La Liga on Wednesday, following up his treble in a 5-2 win at Sevilla four days earlier.The France international brought up 100 Atletico goals in all competitions with his first of the game before going on to reach 15 La Liga strikes for the term, with only three players more prolific this season – Iago Aspas, Luis Suarez and Lionel Messi. Article continues below Editors’ Picks Williams case shows Solskjaer isn’t holding Man Utd’s youngsters back – he’s protecting them Goalkeeper crisis! Walker to the rescue but City sweating on Ederson injury ahead of Liverpool clash Out of his depth! Emery on borrowed time after another abysmal Arsenal display Diving, tactical fouls & the emerging war of words between Guardiola & Klopp With 13 goals in all competitions since Costa’s return from Chelsea, Griezmann’s strikes have helped Atleti cut Barca’s lead at the top of La Liga to four points ahead of Sunday’s showdown between the top two at Camp Nou, although Ernesto Valverde’s men first face Las Palmas on Thursday.And although Griezmann’s stunning goalscoring shone in a comfortable win over Leganes to warm up for Barca, Simeone was keen to hail Atletico’s collective efforts.”The season until December had been very good for the team,” Simeone told a post-match news conference. “Costa’s presence not only improved Griezmann’s moment, but that of the team. For his tenacity, courage and what he transmits to the team.”The team is in a good moment, and from humility we go match by match as always. “The moment is good for the team, we need to focus on continuing to improve as a team. The team was more forceful than in Sevilla at the end of the game [where Atleti conceded two late goals] – that speaks of an improvement.”Now to prepare the Barcelona match in the best way, against a rival who has never lost. It’s a nice challenge.”We score as a team, we celebrate as a team!Atlético fans, we’re a family! #AtletiLeganés #AúpaAtleti pic.twitter.com/DNeTipBMwV— Atlético de Madrid (@atletienglish) February 28, 2018Griezmann’s relationship with Atleti supporters has occasionally been sticky, with the striker criticised for ‘shushing’ fans during a 1-0 win over Valencia at the start of February.”People are passionate, they are behind what they perceive,” Simeone said. “They want to win, and if they see players who give everything, run, work and score they will always be applauded. It happens at Atletico and in all the teams of the world.”[Griezmann] had other seasons playing at this level. He is an extraordinary player, he has shown it more times, and the team is accompanying him to perform at this level. The passes of Koke, Filipe [Luis] and Costa were fantastic.”
It was an eventful week for several former Cowboys in the NFL, let’s take a look at the top five storylines for Pokes in the pros.1. Rudolph Rebounds After Rough StartMason Rudolph returned from a three-week absence following his concussion and Pittsburgh’s bye week, but showed a little bit of rust on Monday night. Rudolph was actually a reviewed reversal away from throwing two interceptions in his first four passes and found his Steelers down 14-0 to the winless Dolphins. But he was able to get into rhythm and dug the Steelers out of the hole throwing for a new career-mark 251 yards and two touchdowns.And he did it with the long ball.James Washington was able to haul in just one of his six targets on the night for 21 yards. But he did earn a little street cred with the coaching staff with this nasty block at the goal line.Mike Tomlin approves of Washington’s block pic.twitter.com/Xhe0P47TlA— Kyle Cox (@KyleCoxPFB) October 29, 20192. Chris Carson Runs MeanSince missing the majority of this rookie season with a leg injury, Carson has been among the most productive rushers in the NFL..@ccarson_32 and the @Seahawks running game are steady hustlinn’. #GoHawks pic.twitter.com/NwWVFILOVO— Seahawks PR (@seahawksPR) October 16, 2019Carson, who finished fifth in the NFL rushing last season, is on pace for the same finish as he currently ranks No. 5 in rushing yards at 659 through eight games.He added to that total on Sunday, as the Seahawks beat the Falcons on the road 27-20. Carson recorded 90 yards on 20 carries including a couple of violent plays from scrimmage.He had this one with a broken tackle followed by a truck-stick.Wouldn’t be surprised if Chris Carson is undefeated lifetime in the Oklahoma drill pic.twitter.com/jBFNPy2Lvl— Ian Hartitz (@Ihartitz) October 28, 2019And then this nasty trot to pay dirt.Chris Carson 1 Yard Touchdown 🔥 #Seahawks @ccarson_32 pic.twitter.com/xLzEyBxb5Z— SeahawksUnited (@SeahawksUnited_) October 27, 2019Fellow Seahawk and former Cowboy, Tre Flowers was inactive due to a neck injury.3. E-Man Adds to His Sack TotalThe former Cowboy sack leader is now the Chiefs’ sack leader.BIG-TIME sack Emmanuel Ogbah 😤#GBvsKC | #SNF(via @NFL) pic.twitter.com/kN1G7aiznb— PFF (@PFF) October 28, 2019 After his crucial third-and-goal sack of Aaron Rodgers on Sunday night, Ogbah’s sack total sits at 4.5, the most among Chiefs despite starting just two games in Kansas City. He’s just one away from his season-best mark of 5.5.Ogbah ended the night with four total tackles, a tackle of loss and that sack of Rodgers, but the Chiefs would fall to 5-3 sans their quarterback Patrick Mahomes.4. Russell Okung Makes 2019 DebutThe former OSU All-American and first-round pick made his 2019 debut on Sunday in the Chargers’ 17-16 win over the Bears. He was sidelined for the first seven weeks of the season after being diagnosed with a pulmonary embolism in June, a serious medical condition that put his football career in jeopardy.In his absence, Los Angeles started 2-5 and Philip Rivers, whose blindside Okung is in charge of protecting, was sacked 13 times.Okung returned to practice two weeks ago and was able to make his return on Sunday against the Chicago Bears. His first assignment? Lining up opposite four-time Pro Bowler Khalil Mack who he successfully staved off from his QB.It wasn’t all smoothing sailing. Okung left in the fourth quarter with a calf injury, and Rivers was subsequently sacked for the first time all day — at the hands of Mack.5. Raiders Waive Justin Phillips Following Season-Ending InjuryThe rookie linebacker saw action on special teams in four games this season with the Raiders, including four total tackles two weeks ago during the Raiders’ loss to the Packers.But after seeing a season-high 21 snaps on special teams on Sunday, an injury ended Phillip’s short tenure in the Bay area.Gruden says Justin Phillips has a knee injury and is out for the season. Raiders will look to shore up the LB spot in the next 48 hours.— Jimmy Durkin (@Jimmy_Durkin) October 28, 2019On Monday, Phillips was waived by Oakland, who signed linebacker Brandon Marshall in a corresponding move. Phillips suffered a knee injury that will reportedly will end his 2019 season.I Can’t Lie This Hurts! Only thing I can do is take this as a plan in action and build from it. I ain’t taking nun less after this. It’s Up There Next SZN! #underdog 🐾 pic.twitter.com/Eb4VPdFDj6— Justin Phillips (@Phillips_Era19) October 30, 2019 While you’re here, we’d like you to consider subscribing to Pistols Firing and becoming a PFB+ member. It’s a big ask from us to you, but it also comes with a load of benefits like ad-free browsing (ads stink!), access to our premium room in The Chamber and monthly giveaways.The other thing it does is help stabilize our business into the future. As it turns out, sending folks on the road to cover games and provide 24/7 Pokes coverage like the excellent article you just read costs money. Because of our subscribers, we’ve been able to improve our work and provide the best OSU news and community anywhere online. Help us keep that up.
Posted on August 30, 2010June 21, 2017By: Janna Oberdorf, Communications Manager, Women DeliverClick to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to share on LinkedIn (Opens in new window)Click to share on Reddit (Opens in new window)Click to email this to a friend (Opens in new window)Click to print (Opens in new window)At today’s session on “Policy and advocacy tools,” panelists presented on web-based and new media options for disseminating maternal health research and messages. Though online technology is an often-untapped resource for the maternal health field, the panelists laid out specific ideas and strategies that have the potential to catalyze policy change.Panelists discussed:• Leveraging new and online technology for maternal health advocacy and communication; Mari Tikkanen, M4ID• An Atlas of Birth: mapping the global challenges and solutions to maternal mortality; Sarah Neal, University of Southampton• Lives Saved Tool: influencing maternal and child health policy; Koki Agarwal, MCHIP“Maternal health doesn’t have a global movement,” said Tikkanen. “We need these tools to reach out to a broader audience.”It was interesting to hear the panel talk about the need to present evidence in ways that capture attention and provoke action among a diverse array of stakeholders. It’s true. Research is incredibly important. But we also need to take scientific research, like the data used in the Lives Saved Tool (LiST), and make it accessible. Data visualization and creative maps, like those created in the Atlas of Birth, are fantastic ways to capture policymakers and express complex issues quickly.But maps are a natural next step for researchers and academics. What else can we be doing? We can be blogging, updating our Facebook pages, tweeting, downloading iPhone apps, sending text alerts, and more. I am a strong supporter of all new media initiatives, but I think it’s important to remember the difference between awareness-raising and advocacy. Though raising awareness is a step towards advocacy, we should be mindful that our social networking and online tools have an intended impact on policy change. It is not enough to just exist on social networks; we must strategize and use tools that benefit our organizational mission and the broader maternal health cause. And we must tailor our messages to specific audiences.We also need to work hard to combat those who think online tools are trivial. Betsy McCallon of the White Ribbon Alliance and moderator of the session gave a great example: “In the US, where global development aid support is sliding, policymakers need to hear from their constituents that these issues are important,” she said.I encourage maternal health organizations who look down on new media, or who fear the rapid pace and inherent transparency, I encourage you to join the movement. Social media and online tools put the power in the hands of the people. It’s our job, as maternal health advocates, to make sure that power is maximized and targeted.Stay up to date with the conference happenings! Follow the Maternal Health Task Force and EngenderHealth on Twitter: @MHTFand @EngenderHealth. The conference hashtag is #GMHC2010.For more posts about the Global Maternal Health Conference, click here.For the live stream schedule, clickhere.Check back soon for the archived videos of today’s presentations.Share this: ShareEmailPrint To learn more, read:
World Cup Petkovic denies deliberate Neymar fouls as Switzerland rough up Brazil Jamie Smith Last updated 1 year ago 06:48 6/18/18 FacebookTwitterRedditcopy Comments(0) Getty Images World Cup Brazil v Switzerland Brazil Switzerland Neymar The Swiss coach claims his side did not set out to target the Paris Saint-Germain star, although he was was awarded 10 free-kicks during a 1-1 draw Neymar was not deliberately targeted with aggressive fouls in Brazil’s opening World Cup match, according to Switzerland coach Vladimir Petkovic.The Brazil star was awarded 10 free-kicks – more than any player in a World Cup match since 1998 – during Sunday’s 1-1 Group E draw at Rostov Arena and appeared to be limping in the second half.Valon Behrami, Fabian Schar and Stephan Lichtsteiner were all booked for fouls on Neymar, but Petkovic insists Switzerland did not set out to target the Paris Saint-Germain forward, who started his first game since February after recovering from a foot injury. Article continues below Editors’ Picks Perfection from Pulisic: Chelsea’s Captain America has arrived in the Premier League Why always Raheem? ‘Unplayable’ Sterling setting a standard Man City’s other stars need to match ‘There is no creativity’ – Can Solskjaer get Man Utd scoring freely again? ‘Everyone legged it on to the pitch!’ – How Foden went from Man City superfan to future superstar “No, most of the duels were perfectly clean and very often we had one-on-ones with Neymar,” Petkovic told a news conference.”One of the key ingredients [of the result] was to neutralise him but there are different players in the Brazil squad who have great quality and they have shown that on the pitch.”Of course, it was a strategic, psychological type of discipline and I am very proud of the discipline with which my team played and they did everything we talked about, which was very important in one-on-one situations but also collectively against this opponent.”We were not actually able to implement it in the first half and that invited Brazil to be dangerous. As far as yellow cards are concerned there were a bit too many. I didn’t see any bad fouls. My team played it very cleverly. We did some good things and I’m pleased.”I hope people will start taking notice of us. Sometimes there is a lack of recognition and that’s a pity because we played very well and only conceded once. We demonstrated that this team always believes in itself and we will continue to play with that consistency.”Tomorrow we will recover a bit and then focus on the very difficult match coming up against Serbia.”10 – The last player to be fouled more in a #WorldCup game than Neymar v Switzerland (10) was Alan Shearer in 1998 (11 v Tunesia). Down. pic.twitter.com/5uE51q1Irx— OptaJohan (@OptaJohan) June 17, 2018Brazil felt Miranda was fouled by Steven Zuber as he headed home the equaliser for Switzerland.Gabriel Jesus also saw a penalty appeal fall on deaf ears after tangling with defender Manuel Akanji in the penalty area, with Petkovic backing both decisions.”The opponent’s defensive players were not well-positioned – it wasn’t a foul,” Petkovic said of Switzerland’s leveller.”I didn’t see the penalty but I don’t complain because we have referees outside and inside the field. I saw it as a very clear situation.”
World Cup Bizarre excuse offered for Marcelo injury which has Real Madrid star sidelined for Brazil Stephen Creek 20:00 6/28/18 FacebookTwitterRedditcopy Comments(5) Getty Images World Cup Brazil Brazil v Mexico Mexico Serbia v Brazil Serbia Marcelo The back spasms which forced the defender out of a win over Serbia may have been caused by a hotel mattress, according to the Selecao’s team doctor Brazil’s team doctor has said a hotel mattress may have caused the back spasms which forced Marcelo off the field during a 2-0 victory over Serbia.The Real Madrid left-back was substituted after just 10 minutes of the game and early analysis suggested he was suffering from back problems.Dr Rodrigo Lasmar told reporters after the game that he was optimistic over the 30-year-old’s chances of being fit for Brazil’s round of 16 clash with Mexico on Monday, but Marcelo’s sleeping conditions might need to be assessed. Article continues below Editors’ Picks Perfection from Pulisic: Chelsea’s Captain America has arrived in the Premier League Why always Raheem? ‘Unplayable’ Sterling setting a standard Man City’s other stars need to match ‘There is no creativity’ – Can Solskjaer get Man Utd scoring freely again? ‘Everyone legged it on to the pitch!’ – How Foden went from Man City superfan to future superstar “It is still too early to make an accurate diagnosis,” said Dr Lasmar. “The injury may be related to the hotel mattress.”Although our expectation is good, but we have to be calm and wait for the next few days.”Marcelo missed three Real Madrid matches due to a hamstring injury in February but has been otherwise largely injury free in recent years.Dr Lasmar said that as long as a serious injury did not emerge, he would treat Marcelo’s pain in order to prepare him for the Mexico game.”Marcelo is medicated and with medication the tendency is that the response is good and that he can play,” he said. “The important thing is that there is no injury.”They were muscle spasms. Once he feels good to train, he will return and immediately be ready to play.”There is no recovery period.”
BATHURST, N.B. – A city council in northern New Brunswick is staying tight-lipped about changes to a contentious Halloween bylaw that puts an age limit on the pursuit of sugary loot and sets a curfew for anyone in disguise.Bathurst Coun. Samuel Daigle confirmed that amendments easing an existing Halloween bylaw passed final reading during a council meeting Monday night, but declined to comment further.“The communications director asked us not to comment on anything,” he said Tuesday. “Each time we say anything it turns into a circus.”Bathurst spokesman Luc Foulem said in an email Tuesday that the mayor and councillors “will not be making any further comments” regarding the Halloween bylaw amendments, which have received international attention.The new rules ban trick-or-treating for anyone older than 16 and set an 8 p.m. curfew for all, relaxing the old bylaw forbidding teens over age 14 from collecting candy door-to-door with a 7 p.m. cut-off.The bylaw also prohibits anyone from wearing a facial disguise in public after curfew. Anyone spotted donning a zombie mask or a witch’s veil after 8 p.m. can be fined up to $200.It also stipulates that Halloween is to celebrated on Oct. 31.While many towns and cities have issued Halloween-related policies or guidelines to protect little ghosts and goblins or step up police patrols, a bylaw restricting trick-or-treating and enforcing an early curfew is an unusual step.Although the changes in Bathurst relax existing restrictions, the bylaw has generated intense controversy — the city’s deputy mayor wants it should be scrapped altogether. Kim Chamberlain calls it an overreach for city councillors to impose Halloween rules.Bathurst police say they’ll use common sense enforcing the Halloween bylaw.“If some child is walking around at 8:05 p.m. and has a mask on, we’re not necessarily going to give them a ticket,” Const. Jeff Chiasson said in an interview Monday. “But if we do find people over the age of 16 throwing apples or stealing candies from other kids or things like that, that’s where the imposition of the fines would be put into place.”The bylaw gives police a tool to prevent and stop mischief, he said, adding that fines would be used only as a last resort.“I think the spirit of this is to prevent any mischief,” he said.— Story by Brett Bundale in Halifax
Vladimir EvtushenkovVladimir Evtushenkov, the chairman and majority owner of Russian energy to media conglomerate Sistema has been arrested and charged with money laundering related to the acquisition of Bashneft, the major energy company in the Republic of Bashkorostan.Sistema issued a statement saying that the company’s management believed the acquisition of the Bashkorostan group was legal and transparent and that it was cooperating with the investigation. It said it would use all legal means to defend its position.Under Russian law Evtushenkov could face up to 10 years in prison and a fine of RUB1 million (€20,000) if convicted.Sistema’s shares lost over a third of their value on the news, while shares in telecom subsidiary MTS fell by about 8%.Sistema is Russia’s largest publicly traded diversified holding company, operating across the telecoms, technology, energy, aerospace, banking, retail, media, tourism and healthcare sectors, with reported revenues of US$8.8 billion (€6.8 billion) for the second quarter and total assets of US$45.2 billion.Sistema Mass Media, in which the holding company has a 85.7% stake, owns and manages pay TV channels provider Stream, Russian World Studios, Maxima and TsTV.Sistema also holds an effective majority stake in telecom and pay TV provider MTS, the country’s largest service provider by revenue. Stream is 55% owned by Sistema and 45% owned by MTS. Evtushenkov owns a 64.2% stake in Sistema and his personal fortune is estimated at around US$9 billion.
UT Arlington Culture of Entrepreneurship Inspires North Texas Community regions: Dallas Through a number of partnerships within the business community, University of Texas at Arlington – College of Business has created a culture of entrepreneurship that benefits students, faculty and the city at large.When it comes to the UT Arlington entrepreneurship culture, both students and faculty benefit from the school’s commitment to inventiveness. Many faculty members at UTA and the School of Business have already demonstrated success as inventors. According to UTA vice president for research Duane Dimos, twelve faculty members across the university have been named fellows of the National Academy of Inventors (NAI). Such proven success in innovation can no only be passed directly on to students, but also helps attract new faculty members. Most recently, former AT&T CTO Krish Prabhu has taken the role of research professor in the Department of Computer Science and Engineering.For students interested in entrepreneurship, UTA has designed a specific curriculum to support an ecosystem of innovation among student, faculty and alumni. At the College of Business, entrepreneurship certificate programs give students the opportunity to develop the skills necessary for turning an idea into a business. The entrepreneurship certificate can be earned as part of either an undergraduate or graduate degree and includes courses such as Entrepreneurship in the Arts, Engineering Entrepreneurship, Social Entrepreneurship and Innovation and more.Also integral in supporting the UTA innovation economy is the existence of several innovation spaces, such as the FabLab, the first MIT-affiliated FabLab at a Texas university, supporting project-based and hands on STEAM engagement. Another form of support for the university’s entrepreneurs comes in the form of Innovation Events and Pitch Competitions, such as the annual InnovationDay@UTA event sponsored by the Office of Research or the CreaTEc Challenge which offers more than $10,000 in cash prizes and resources. Last Updated Jul 5, 2017 by Alanna ShafferFacebookTwitterLinkedinemail About the AuthorAlanna ShafferStaff Writer, covering MetroMBA’s news beat for Atlanta, Houston, and Dallas.View more posts by Alanna Shaffer RelatedUTA Graduate Programs Rise in National RankingsThe University of Texas at Arlington – College of Business has recently risen in national rankings, with over 20 graduate-level programs ranked among the best in the nation by U.S. News & World Report this year. The latest ranking from U.S. News & World Report featured 100 graduate programs in seven…April 27, 2016In “Featured Region”UTA College of Business Named Best Business School by Princeton ReviewThe University of Texas at Arlington – College of Business was recently named one of the “best” business schools in the Princeton Review’s 2017 “Best 294 Business Schools”. “We recommend The University of Texas at Arlington, College of Business as one of the best to earn an MBA,” said Princeton Review…December 7, 2016In “Featured Region”Mays Professor Honored with Lifetime Achievement Award for Scholarship ContributionsDuane Ireland, Executive Associate Dean of the Texas A&M University – Mays Business School, has recently been awarded with the Lifetime Achievement Award for research and scholarship contributions. Ireland is the current Executive Associate Dean at Mays and also serves as University Distinguished Professor while holding the Benton Cocanougher Chair in…March 15, 2017In “Featured Region”
Source:https://www.lunduniversity.lu.se/article/new-view-on-the-mechanisms-of-how-the-brain-works Reviewed by Alina Shrourou, B.Sc. (Editor)Apr 29 2019After a series of studies, researchers at Lund University in Sweden, together with colleagues in Italy, have shown that not only one part, but most parts of the brain can be involved in processing the signals that arise from touch. The results open the way for a new approach to how the brain’s network of neurons processes information, and thereby the mechanisms by which the brain works.The researchers conducted in-depth analyses of how touch signals are transferred and processed in neurons of various parts of the brain and the latest studies have been published in Cell Reports and Frontiers in Cellular Neuroscience. The experiments were conducted on anesthetized rats.”We immediately realized that our findings deviated strongly from the accepted view that different parts of the brain are responsible for different specific functions”, says Henrik Jörntell, one of the researchers behind the study.The studies shed new light on how the brain processes signals about our experiences of the surrounding world.”According to a prevailing view of the brain, known as functional localization, the brain works like a set of switches: different parts of the brain are responsible for different functions. This theory is certainly easy to comprehend, but when we measure the activity levels in individual neurons, we get a different picture, which indicates that functions are in fact processed more globally by the whole brain”, says Henrik Jörntell.Knowledge of how the brain manages information down to the individual neuron level is important to understand how neurological diseases occur, as they often comprise a disruption in the transfer of information between neurons.The imprint of touch signals in the brainThe researchers used methods that enabled them to observe very precisely which touch signals were sent between various neurons in the brain’s network. Among other things, they generated touch signals through a finger prosthesis with synthetic skin sensitivity, a method which enabled them to send exactly the same signals in each experiment. Thanks to this new approach, the researchers were able to analyze how the touch signals were processed by individual neurons in various parts of the brain with a significantly higher resolution than was previously possible.Related StoriesWearing a hearing aid may mitigate dementia riskMercy Medical Center adds O-arm imaging system to improve spinal surgery resultsResearchers measure EEG-based brain responses for non-speech and speech sounds in children”The experiments showed that all parts of the brain we investigated were involved and processed the signals generated by touch, and that the differences in information between different neurons mean that they complement one another to create a rich picture, or perception”, says Henrik Jörntell, brain researcher at Lund University.One neuron, several functions and a single networkThe researchers’ explanatory model is that all information processing is conducted as though through a single network and that the neurons in the brain, in practice, have partially different functions from one situation to another.”Each individual neuron is involved in a large number of different functions. As it is closely tied to a very large number of other neurons, the function that one neuron has in a specific situation will be determined by what the other neurons with which it is connected are doing at the time”, says Henrik Jörntell.He thinks this could explain the previously baffling observation that minor brain injuries or loss of neurons often go unnoticed.”The brain’s network learns to solve the same tasks by creating partly new collaborative groups of neurons, which enables it to bypass damaged neural tissue with no measurable loss of function. I believe that these findings could mean a new world of promising treatment potential for many different conditions. As there is often an extensive latent brain capacity left in cases of major brain injury, one can imagine that a greater recovery could be achieved if we could teach the brain to form new collaborative groups of neurons”, says Henrik Jörntell.
Source:http://www.ucr.edu/ Reviewed by James Ives, M.Psych. (Editor)May 10 2019A stroke treatment developed by researcher Byron Ford at the University of California, Riverside, has moved toward clinical trials.The treatment focuses on neuregulins, a family of naturally occurring proteins that has shown promise for treating stroke, a leading cause of death in the United States and the major cause of long-term disability.During stroke, blood supply to the brain is interrupted. Most often, an artery to the brain gets blocked by a clot or a blood vessel ruptures. With no blood — and therefore no oxygen or nutrients — reaching the brain, cells in the brain begin to die locally, at the “core,” within a couple of hours. Subsequently, the core cells burst and release their components into the surrounding area, which then experiences a dramatic inflammatory response. This area, called the ischemic penumbra, dies over the course of several hours or days. Neuregulin-1, or NRG-1, one of four proteins in the neuregulin family, prevents this inflammation and cell death.”Cells in the core die by getting overexcited and exploding,” said Ford, a professor of biomedical sciences at the UCR School of Medicine, whose company, Brain-Gen, has patents for the use of NRG-1 to treat stroke. “Cells in the ischemic penumbra die by committing suicide. This happens, we believe, to prevent the whole brain from dying. An analogy: imagine a grenade is flung into a crowded theater, and a few people throw themselves on the grenade. They will die, but due to their sacrifice, others may very likely be spared.”Brain-Gen is co-owned by his brother Gregory Ford, a neuroscientist and the dean of the College of Arts and Sciences at Fort Valley State University in Georgia. Byron Ford explained that Zensun Biotech, a Shanghai-based Chinese company with which Brain-Gen has recently partnered, has patents to use a particular form of neuregulin, called Neucardin, to treat heart failure. Zensun Biotech does not have patents, however, for Neucardin’s use in clinical trials for stroke. Brain-Gen tested Neucardin and found it works for stroke in animal models.The two companies have signed an agreement to collaboratively move Neucardin toward clinical trials for stroke and to form a joint venture. The new company plans to approach the Food and Drug Administration, or FDA, to expand the use of Neucardin for stroke and to explore the possibility of securing funding from the National Institutes of Health, or NIH, with the aim of joining its StrokeNet clinical trials program.Related StoriesStudy explores role of iron in over 900 diseasesNew approach to post-stroke rehabilitation proposedUse of statins linked to reduction of mortality risk in dementia patientsInvolving more than 200 hospitals in the country, StrokeNet conducts small and large clinical trials and research studies to advance acute stroke treatment, stroke prevention, and recovery and rehabilitation following a stroke.”To our advantage, Zensun has already completed phase I and phase II clinical trials for heart failure and shown that Neucardin is safe and improves heart function in patients,” Ford said. “A stroke is like a heart attack in the brain. If the FDA says we can cross-reference Zensun’s data for approval to treat stroke, this would greatly expedite matters as we apply to become part of the NIH StrokeNet.”Each year, nearly 800,000 Americans have a stroke, of which about 140,000 die. The “Stroke Belt,” an area in the southeastern United States and Mississippi Valley, has the highest rate of stroke mortality in the country.Currently, the only FDA-approved drug to treat stroke is tissue plasminogen activator, or t-PA, which melts the clot. It has no effect on brain cells, however, and can be used only within a three-hour window from the witnessed time of stroke onset, beyond which t-PA damages blood vessels and causes bleeding. Further, only 3%-5% of stroke patients qualify for t-PA due to the limited time window and access to primary stroke centers. In contrast, Neucardin can be given to a patient more than 12 hours after a stroke and has been shown to be safe in patients.Ford proposes that Neucardin be administered intravascularly to the patient along with t-PA to offer protection to the brain and potentially block t-PA’s negative effects that lead to bleeding in the brain.”Neucardin can possibly be delivered in an ambulatory setting due to its relatively safe profile,” he said. “It can be given to the patient even before it has been determined if a stroke took place. It can also be delivered days following stroke to stimulate repair and regeneration in the brain. All this significantly boosts our hope for treating stroke.”